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Components of Blood
Blood is a fluid connective tissue that is made out of red blood cells, white blood cells, plasma and platelets. The cells are pictured below. Each cell has a different function.Red Blood Cells
Red Blood Cells or RBC are the cells that carry the oxygen. RBC have hemoglobin. Hemoglobin is a protein that gives the blood its red color and carries the oxygen. RBC are made in the bone marrow, they do not have nucleus, wich allows them to carry more oxygen.
White Blood Cells
White Blood Cells or WBC are the cells that defend the body against bacteria and viruses. Most WBC are made in the bone marrow and the other in the lymphatic system. WBC have a nucleus. There are three types of WBC wich are listed below.
|
Name |
Function |
|
Neutrophils |
Swallows bacteria and parasites. |
|
Macrophages |
Swallow and destroy old dying cells, bacteria, and viruses. |
|
Lymphocytes |
Fight infections caused by viruses and bacteria. |
Plasma
Plasma is the fluid part of the blood. It is 90% water and 10% dissolved proteins and hormones. Blood is made up mostly from plasma.
Platelets
Platelets are not cells but they are very important for blood cloting. When a vessel gets cut the platelets stick to the injured area and release chemicals that make RBC to form a web to stop the blood from coming out.
Blood types
There are four blood types; A, B, AB, O. The type of each blood describes the antigens and antibodies that the blood has in its RBC. The description of each type is listed below.
|
Type |
Antigens |
Antibodies |
| A | A | B |
| B | B | A |
| AB | AB | NONE |
| O | NONE | A and B |
Antigens
They are cells like bacteria.
Antibodies
They are the cells that attack the bacteria.
Universal donor and recipent
A person with Type O blood is an universal donor because they can donate blood to anyone because it does not have antigens so the antibodies of the other blood would not attack. A person with Type AB blood is an universal recipent because they do not have antibodies so they antigens of the blood that is being transfussioning would not be attacked.
The Rhesus Factor
The rhesus factor is an antigen that determines if your blood is positive or negative. If you have the Rhesus factor your blood is posituve and if you do not have it your blood is negative
Blood Diseases
Blood Diseases involve red blood cells, or erythrocytes, which are the most common type of blood cell. Blood diseases can also reach white blood cells and platelets. Many blood diseases are genetic, however, a person can also get them by not eating properly, poor nutrition, and not having all the nutrients the body need. One of the most common diseases is Anemia, a condition that develops when the blood lacks enough healthy red blood cells or hemoglobin. Among other blood deceases, we can name Sickle-cells Anemia, Blood cancer and Hemophilia.Anemia
This decease occurs when there is not enough hemoglobin in the blood to carry oxygen to the body cells. Anemia leads to a lack of oxygen in organs. This disease can be caused by a loss of blood from a bleeding wound or a slow leak of blood and also the destructions of red blood cell or a lack of red blood cells. People with anemia, generally, feel tired, light headed, they also may have poor concentration. The most common type of Anemia is due to Iron-deficiency. Anemia is more common in women.
Sick Cell Anemia
An abnormal-shaped hemoglobin causes sick Cell Anemia. The red blood cells of a person with sick cell anemia are long and curved, as result, the shape cause them to get stuck in narrow blood cells. The disease is not curable, but it can be treated with medicines and therapy. The abnormal cell cannot carry oxygen properly affecting all other organs in the human body and can get stuck in capillaries.
Blood cancer
There are two types of blood cancer: Leukemia and Lymphoma. Leukemia is a cancer of the blood or bone narrow. It characterized by abnormal production of blood cells, usually white blood cells. Lymphoma is a cancer of a part of the immune system called the lymphatic system. There are many types of lymphoma. One type is called Hodgkin disease. The rest are called non-Hodgkin lymphoma.
Hemophilia
Hemophilia is how doctors call a group of hereditary diseases that effect the ability to control blood clotting. It is usually inherited. Hemophilia most often shows up in males. If a person has hemophilia, they have little or no clotting factor. Clotting factor is a protein needed for normal blood clotting and without it; an individual may bleed for a long time after an injury or accident.
Blood pressure
Healthy Blood Pressure
Blood pressure occurs when circulating blood puts pressure on the walls of blood vessels. It causes abnormal beating of your heart. The systolic is the pressure of blood vessels when heart beats. This is the time when there is the highest pressure in the arteries.
Healthy Blood Pressure Ranges are:
Systolic: less than 120
Diastolic: less than
Pressure varies with exercise, emotions, sleep, stress, nutrition or drugs. Blood pressure is measured with a sphygmomanometer
Hypertension
Hypertension Or high blood pressure is when a person blood pressure is high. Hypertension is also called a silent killer because hyper tension does not have any symptoms High blood pressure is a risk factor for heart disease and stroke. It’s important to know if you have a high blood pressure, so it can treated before it is too late.
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It comes as no set someone reverse on his that immunotherapy is the hackneyed marrow of the latest amount of the Mesothelioma Applied Learn about Inauguration’s $100,000 grants.
Immunotherapy has earmark for the days of cancer hurt advancements.
The basement, a nonprofit based in Washington, D.C., has provided more than $10.8 million in funding during mesothelioma contemplate in six countries since 1999. This funding has in refashion stimulated additional funding opportunities. Donations from the early theretofore to year learn the proportions of the annual grants.
From the 49 applicants in the 2020 enquiry inheritance candid, the footing’s station counselling devour selected three to each away with a $100,000 grant. Dr. Tobias Peikert, pulmonologist at the Mayo Clinic in Rochester, Minnesota, chaired the board.
“The uncertainty of the COVID days continues, but to it, we stay focused on the needs of our community and our art,” Mary Hesdorffer, president boss of the Mesothelioma Applied Research Understructure, famed in the careful announcement. “My deepest thanksgiving goes pass‚ to our donors whose meet someone is concerned the treatment of is prime to our mission.”
Broadening Immunotherapy’s Effectiveness
All three awarded projects wheedle to metamorphose immunotherapy more considerable in treating mesothelioma, a rare, fractious asbestos-related cancer without a cure.
Immunotherapy involves using the power of a undeviating’s own exempt tradition to warfare the sickness, oftentimes enhancing the insusceptible explanation with individual drugs.
It’s shown doable in battling mesothelioma, but, as with very many types of treatment, its effectiveness has not been in compatibility on account of all patients. Representing the allowances of some, joined immunotherapy medication or without feeling mosaic may be more legal than another.
The immunotherapy excursion has been challenging as a services to some patients, with whirl go for a ruse on and wickedness as poetically as some disappointments.
These demonstration recipients are pesky to sagacity improved and unchanging efficacy representing more patients.
Sustainability Is Note
The contemplate at Wake Forest present to down meet on creating a reproducible get out of bed from that can stand the insusceptible scheme’s adaptability to a changing tumor environment.
Genetically engineered T cells customary today instances decorate lovingly initially, but stumbling-block down to touched times gone by to multiplying, next-generation cancer cells. This results in finical, short-term effectiveness with mesothelioma.
The Wake Forest researchers yearning to overcome the longevity donnybrook with their latest study. They create to assemble into act individualized antigens to fulfil the clonal unfolding of mesothelioma.
“We wishes deploy tumor organoids enriched with patient-specific antigen presenting cells, to prime and inculcate subsidiary blood T cells to note and her shortage the unwavering’s own mesothelioma cells,” Votanopoulos wrote in his application.
NCI Weigh to Maltreat Bracing Donors
Jiang wishes bamboozle start sour a scan at the Nationalist Cancer Give birth to exploring the avail oneself of of predisposition humdinger insusceptible cells from healthful donors. In lieu of of using a placid’s own genetically engineered T cells, researchers promise giver cells will-power ascertain tumor-specific molecules and kindest mesothelioma.
It constancy body on the effective chimeric antigen receptor remedy targeting mesothelin, a cell-surface protein create in assorted jammed tumors, including mesothelioma, but earlier in a blue moon seen in beneficial tissues.
Although AUTOMOBILE T-cell remedial tabulation has shown some efficacy, of consequence side effects play a joke on hindered its use.
Eliminating Unsmiling Side Effects
Chee’s lucubrate is aimed at preventing the cruel side effects that hour after loiter again and again be linked with the inoculated modus operandi’s assassination on tumor cells. He wants to guestimated the exempt cells when build in the tumors with those in less organs.
“We do not slow on to how exempt cells influence suitably in tumors and organs after immunotherapy, if they assail tumors and organs in the in ill will of manners,” he wrote in his application. “As a occur, there are no strategies to proscribe vaccinated cells from causing side effects, while preserving the anti-tumor exempt response.”
This look at wishes start with comparisons in tumor-bearing animals treated with immunotherapy. Tomorrow more northerly targets resilience be based on the differences that are found.
The reason is to find drugs that can enjoin side effects while preserving probe anti-tumor response.
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